In theory, there is no difference between theory and practice. In practice, there is.

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Heyo, welcome back! While the World Cup might be coming to an end, we’re just getting started with the summer holidays #bringoutthesunglasses

Here’s a taste of what we’re serving today:

  • Why Does Hair Turn Grey? 🧑‍🦳

  • PLUS: Bond Market Politics, Ireland’s First People, and The Philosophy of Romeo and Juliet ❤️

MEDICINE

Why Does Hair Turn Grey? 🧑‍🦳

For many, the first grey hair feels like a milestone, or a shock! But why do strands lose their colour with age? And why do some people go grey in their 20s while others keep their natural shade into their 60s?

Hair colour depends on melanin production in hair follicles, which changes with age and genetics. Scientists now understand more about the stem cells, stress, and immune responses that contribute to this very visible sign of ageing.

💡 Things to consider

  • Melanin and follicle stem cells: Hair gets its colour from melanin, a pigment produced by specialised cells in the hair follicle. As we age, the stem cells that replenish these pigment-producing cells gradually die off or become inactive. With fewer cells making melanin, hair grows out grey or white. The process isn’t sudden; each strand cycles between colour and reduced pigment before eventually turning fully grey.

One possible structure of eumelanin. Eumelanin is one of the five basic types of melanin

  • Genetics and early greying: Genes play a major role. Family history often predicts when a person will start greying. Certain populations tend to grey earlier than others, and some inherited conditions can accelerate the process. While vitamin deficiencies and smoking can influence hair colour, genetics is by far the strongest factor.

Sheldon Cooper better watch out… he might end up with grey hair!

  • Stress and the immune system: Recent studies suggest chronic stress can accelerate greying by damaging pigment-producing stem cells in the follicle. Stress hormones, like cortisol, seem to push these cells into overdrive until they burn out. Interestingly, the immune system may also play a role: some autoimmune conditions cause sudden, patchy greying.

🔎 Find out more

🍒 The cherry on top

A QUICK WORD FROM PEPPO TUTORING

PowerUp Fest is A FREE Festival for Legal Careers, where you can expect:

🚀 Top law firms and barristers’ chambers

🚀 Inspiring talks and panels

🚀 CV, application and interview top tips

🚀 Prize draw, DJ set, and much more!

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That’s it for this week! We’d like to thank this week’s writer: Rob Folkard.

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